Adult Neurogenesis in Mammals: An Identity Crisis
نویسندگان
چکیده
منابع مشابه
Adult neurogenesis in mammals: an identity crisis.
The study of neurogenesis in the adult brain is among the most exciting and fastest moving areas of neuroscience today. In contrast to the high rate of neurogenesis in some vertebrates (Nottebohm, 2002), unambiguous evidence for new neurons in normal adult mammals ranging from rodents to primates has been confined to the dentate gyrus and olfactory bulb (Lois and AlvarezBuylla, 1964; Kaplan and...
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processes as dentate gyrus neurogenesis is in mammals, i.e. by learning and cognitive stimulation. Thus, his paper does not acknowledge the existence of evidence that neurogenesis in widespread areas of the nonmammalian brain is subject to the same processes as neurogenesis in the dentate gyrus of mammals. For example, enriched environments enhance adult neurogenesis in nonmammals, just as Kemp...
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New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differenc...
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This review will discuss adult hippocampal neurogenesis in wild mammals of different taxa and outline similarities with and differences from laboratory animals. It begins with a review of evidence for hippocampal neurogenesis in various mammals, and shows the similar patterns of age-dependent decline in cell proliferation in wild and domesticated mammals. In contrast, the pool of immature neuro...
متن کاملNeurogenesis in adult mammals: some progress and problems.
Approximately 40 years after its first report, the addition of neurons to the brains of adult mammals has now been generally accepted. We now know that several endocrine and experiential variables modulate adult neurogenesis. However, several methodological problems in its quantitative study remain. One is the use of low doses of the exogenous marker of cell proliferation, bromodeoxyuridine (Br...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2002
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.22-03-00614.2002